Driss Kettani graduated from the National School of Architecture in Rabat in 2003 and founded the firm Driss Kettani Architecte in 2005, following several collaborations and study trips. He maintains a constant interest in place, culture, and inhabitants as essential starting points for reflection and projects. This approach goes hand in hand with a commitment to modernity and contemporaneity, in a constant quest for creativity and meaning.

His work is characterized by an approach that combines architectural rigor with a search for the sensitive and poetic dimension of architecture. Architecture, he believes, is the framework for understanding our era, which it can help to elevate by offering users a living environment that expresses culture and high aspirations.

In 2006, he won the competition for the Faculty of Multidisciplinary Studies in Taroudant with his partners and friends Saad El Kabbaj and Mohamed Amine Siana. They also designed the Higher School of Technology in Guelmim in 2011. Both projects have been published in numerous international architecture journals and exhibited in New York, Paris, Venice, Milan, and Valletta. The Guelmim project was shortlisted for the Aga Khan Award for Architecture in 2016. His work has also been recognized with the Mimar Sinan Prize in Istanbul in 2016 and the Archmarathon Prize in Beirut in 2015.

Driss Kettani has published articles in various architecture journals and has lectured in Morocco, Italy, Lebanon, the United Arab Emirates, Tunisia, Turkey, Malta, and France. He has served on numerous national and international juries and has also been a visiting professor at the WAVe workshop. from the IUAV University of Venice in 2014, 2019 and 2020 and currently teaches, alongside the activity of his agency, at the SAP+D of UM6P.